臨床薬理学および生物薬剤学

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A Review: Pharmaceutical and Pharmacologic Treatments Used In Covid-19

Sachin M. Mendhi, Sachin M More, Aayush P Nagbhidkar, Mahesh Sarode

Importance: The pandemic of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents an unprecedented challenge to identify effective drugs for prevention and treatment. Given the rapid pace of scientific discovery and clinical data generated by the large number of people rapidly infected by SARS-CoV-2, clinicians need accurate evidence regarding effective medical treatments for this infection. Vaccination is currently the best bet for the prevention of COVID-19. Still, in its absence, there has been considerable interest in repurposing existing therapeutic agents to reduce the severity of the illness and ease the burden on the already strained healthcare systems. This review outlines the current evidence regarding proposed treatments experimental or repurposed, for COVID-19, and gives an insight into the clinical trial landscape for drugs as well as vaccines.