ジャーナル・オブ・オンコロジーの研究と治療

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Advancing Skin Cancer Prevention: Nicotinamide and DNA Repair Enzymes

Eleanor Tung Hahn, Lauren Moy, Ronald Moy

Historically, the public has looked to sunscreen as the primary method for prevention of skin cancer. However, fortunately there have been advancements in chemopreventative care for both precancerous lesion progression of Actinic Keratoses (AKs) and Non-Melanoma Skin Cancers (NMSCs) that have potential to be more patient-friendly for consistent at home use. These measures can be adjunctive therapies to daily broad-spectrum sunscreen or as well as in office procedures. As a whole, the advantage of these newer therapeutics is that they have dual mechanisms of action in that they promote repair of past damage and prevent future malignancies-something that sunscreen alone cannot achieve.