当社グループは 3,000 以上の世界的なカンファレンスシリーズ 米国、ヨーロッパ、世界中で毎年イベントが開催されます。 1,000 のより科学的な学会からの支援を受けたアジア および 700 以上の オープン アクセスを発行ジャーナルには 50,000 人以上の著名人が掲載されており、科学者が編集委員として名高い
。オープンアクセスジャーナルはより多くの読者と引用を獲得
700 ジャーナル と 15,000,000 人の読者 各ジャーナルは 25,000 人以上の読者を獲得
Rambaud Laurence, Gomas Jean-Marie and Reich Michel
Background: Palliative care disclosure and death-facing can be traumatic for patients with advanced cancer. Some of them can suffer a psychotic breakdown that must be differentiated from a terminal delirium. Objectives: To describe a psychiatric side effect from a palliative care announcement called the Alexandrine syndrome. Methods: To illustrate this, we report the case of a patient with no past psychiatric history who, a few days after his palliative state has been announced, presented a major behavioral disorder with violence and paranoiac delusions, heteroagressivity against caregivers and autoagressivity, that could not be explained by a somatic origin. Results: With this case report, we would like to point out the importance of an unreported palliative clinical situation which cannot be explained by an organic substratum. An intense fear of death expressed by the patient with an outburst of defense mechanisms can lead to a brief psychiatric decompensation without any preexisting state of psychosis. Conclusion: The hypothesis of an Alexandrine syndrome should be considered in palliative care in advanced cancer patients experiencing massive anxiety when facing death. This infrequent diagnosis should especially be hypothesized when a patient presents a feature with sudden or recent profound mental disorder following an oncologist consultation with palliative state disclosure. Physical and psychological consequences must not be neglected for patients, as well as disturbing occurrences for the medical team involved. Therefore, oncologists and palliative doctors should be aware of this possibility. Collaboration between psychiatrists and palliative and oncologic teams is recommended to better manage this psychiatric situation.