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Antibacterial Applications of Biodegradable Polymer Matrix Composites with Graphene-Related Materials: A Critical Analysis
Michael Collins
For the first time, the development, processing methods, mechanical properties, and antibacterial activity of biodegradable polymer matrix composites containing graphene-related materials (GRMs) for antibacterial applications are discussed in this review. Chitosan is the most widely used biodegradable polymer for the production of antibacterial GRM-containing composites due to its suitable biological properties and processability. The majority of biodegradable polymers, such as those made from cellulose, gelatin, PVA, PCL, and PHA, have little to no antibacterial properties on their own; However, when combined with GRMs, they exhibit significant antibacterial activity (>70 percent). In vitro and in vivo examinations demonstrate that GRMs functionalization with biodegradable polymers likewise lessens potential GRM cytotoxicity.