分子薬学および有機プロセス研究ジャーナル

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Buccal Film Drug Delivery System-An Innovative and Emerging Technology

Radha Madhavi B, Varanasi SN Murthy, Prameela Rani A and Dileep Kumar Gattu

Now days, an extensive research is being carried out on the design and development of innovative drug delivery systems to improve the safety, efficacy and patient compliance. One such delivery system is the buccal film technology. This technology has emerged as an advanced alternative to the other conventional types of drug delivery systems. It is the proven technology for the systemic delivery of active pharmaceutical ingredients [API’s]. The buccal mucosa is the best suited site for local, as well as systemic delivery of drugs due to its physiological features. The buccal film is an elegant and effective dosage form with improved bioavailability, when compared to other dosage forms as it bypasses the hepatic first pass metabolism. It is the most acceptable and palatable dosage form due to its small size, small dose and thickness of the film. Moreover, it does not require swallowing of the drug, which is most suitable for pediatric as well as geriatric patients. The present article provides insight into various issues like benefits of buccal films, manufacturing methods, evaluation parameters and also reviews on the market potentiality of dosage form and its future scenario on global market as an effective pharmaceutical dosage form.