口腔衛生と健康のジャーナル

抽象的な

Comparison of Plaque Removal Capabilities between Two Dentifrices

Douglas Ralston, Rey Carrasco, Peter L. Jacobsen and Cherie Wink RDH

Objective: To compare the efficacy of a dental gel containing 2.6% Edathamil in controlling dental plaque to that of a commercially available dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, and 0.243% sodium fluoride.

Materials and Methods: Following a baseline examination and index scoring for dental plaque, gingivitis, bleeding, and pocket depths, qualifying adult male and female subjects were randomized into two groups. The subject’s teeth were professionally cleaned and then they were instructed to brush their teeth twice a day (morning and evening) for two minutes with their assigned dentifrice and a soft-bristled, manual toothbrush. Examinations for dental plaque, gingivitis, bleeding and pocket depths were repeated after two weeks and four weeks of product use.

Results: Eight (8) subjects complied with the protocol and completed the study. Compared to the 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride dentifrice group, the 2.6% Edathamil dental gel exhibited statistically significant reductions in all measured parameters, respectively, after four weeks of product use.

Conclusion: The overall results of this double-blind clinical study supports the conclusion that a dental gel containing 2.6% Edathamil is efficacious for the control of dental plaque, and that it provides a greater level of efficacy for the control of dental plaque biofilm than does a dentifrice containing 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride.