当社グループは 3,000 以上の世界的なカンファレンスシリーズ 米国、ヨーロッパ、世界中で毎年イベントが開催されます。 1,000 のより科学的な学会からの支援を受けたアジア および 700 以上の オープン アクセスを発行ジャーナルには 50,000 人以上の著名人が掲載されており、科学者が編集委員として名高い
。オープンアクセスジャーナルはより多くの読者と引用を獲得
700 ジャーナル と 15,000,000 人の読者 各ジャーナルは 25,000 人以上の読者を獲得
Maged L Boules*
Background: Epidural analgesia offers superior pain relief and early mobilization, especially when a local anesthetic [LA] dose is combined with an adjuvant vs. an LA alone.
Objective: The current study compares the analgesic and anesthetic efficiency of dexmedetomidine (1 and 2 μgkg-1) and levobupivacaine, as well as their respective side effects.
Materials and methods: This study was conducted on a total of 60 ASA I-II patients aged between 20 and 70 years, who underwent elective lower limb operations. The patients that received 1 μgkg-1 dexmedetomidine plus levobupivacaine were assigned to Group 1 (n=30) and those that received 2 μgkg-1 dexmedetomidine plus levobupivacaine to Group 2 (n=30).
Results: Group 2 showed a significantly shortened onset time of sensory block, time needed for maximum sensory level and prolonged duration of anesthesia. Postoperatively, the total dose of levobupivacaine used was significantly lower, patients experienced a higher level of sedation and postoperative analgesia. However, Bradycardia and hypotension were more pronounced in Group 2 patients.
Conclusion: Dexmedetomedine 2 μgkg-1 as an adjuvant to epidural analgesia significantly prolonged the duration of anesthesia and provided excellent sedation and postoperative analgesia. Therefore, higher doses of epidural dexmedetomedine are recommended in long surgical operations to avoid delayed motor recovery, bradycardia and hypotension.