当社グループは 3,000 以上の世界的なカンファレンスシリーズ 米国、ヨーロッパ、世界中で毎年イベントが開催されます。 1,000 のより科学的な学会からの支援を受けたアジア および 700 以上の オープン アクセスを発行ジャーナルには 50,000 人以上の著名人が掲載されており、科学者が編集委員として名高い
。オープンアクセスジャーナルはより多くの読者と引用を獲得
700 ジャーナル と 15,000,000 人の読者 各ジャーナルは 25,000 人以上の読者を獲得
Rahul D Upadhyay, Amit Kumar Yadav, Shobha Sonawane, Reshma Goankar, Debasis Dash and Balasinor NH
Spermiation is the final step of spermatogenesis and involves release of mature spermatids from the Sertoli cells. It is a complex process involving displacement and removal of spermatid cytoplasm, formation and degradation of tubulobulbar complexes and progressive loss of adhesive junctions, including ectoplasmic specializations and subsequent phagocytosis of residual bodies by the Sertoli cell. Spermiation occurs in stage VIII of the rat seminiferous epithelium cycle. In spite of the important role played by spermiation process in sperm output to the epididymis, very little is known about this process. To enhance our knowledge of the sperm release biology, we sought to understand the molecular events occurring at the time of spermiation. Towards this aim, we induced spermiation failure condition by 17β estradiol treatment to adult male rats and compared with the normal spermiation. On comparing both the groups, we identified a total of 104 differentially expressed proteins and 23 differentially expressed phosphoproteins by LC-MS/MS analysis and quantitation. Localization and expression of some of the validated differential proteins in the testes highlight their importance during the sperm release. The present study represents an initial step to understand the molecular basis of the process of spermiation.