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Dual Malignancy of Pancreas: A Rare Case Report and Review of Literature

Aniq Gajdhar1*, Selvakumar Balakrishnan1, Anand Vijai1, Palanisamy Nalankilli1, Basavaraju Srikanth2 and Chinnusamy Palanivelu1

Multiple primary neoplasms (MPNs) are found in approximately 5 to 10% of the population which can present within the same organ (infrequent) or can occur in different organs (much more frequent). The presence of MPNs within the pancreas is exceptionally rare, ranging only from 0.06 to 0.2% of all pancreatic tumors. They are also termed as collision tumors, which are comprised of at least two types of cancers within the same anatomical organ. Majority of the available literature on double primary pancreatic tumors is focused on pancreatic duct adenocarcinoma (PDA), either derived from or concomitantly with an intraductal papillary mucinous neoplasm (IPMN) or association between pancreatic neuroendocrine tumor (NET) and IPMN. Simultaneous PDA with NET is extremely rare. We herein, present a similar case of PDA and NET of pancreas.