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Morris DM, Beloni RK, Wofford H and Roslanova E
We investigated the effects of two different oral doses of lactate on blood lactate, bicarbonate (HCO3-) and pH levels and performance of high-intensity exercise in endurance-trained, competitive cyclists. Twelve subjects consumed 120 (L120) or 300 mg lactate/kg bm (L300) or placebo (PL) 80 min prior to performing an exercise performance test consisting of five high-intensity efforts followed by a timed, high-intensity effort to exhaustion. Seventy minutes following lactate ingestion, blood HCO3- increased in L120 by 10% (p=0.03) and in L300 by 9% (p=0.02) with no significant difference observed between lactate treatments (p=0.74). No significant change in blood HCO3- was seen following consumption of PL (- 0.1%, p=0.98). Blood lactate increased by 27% in L300 (p=0.02) with no significant changes in response to PL or L120. No changes in pH were observed due to treatment. Time to exhaustion in the performance test was increased by 14% in L120 (p=0.004) and 26% in L300 (p=0.001) when compared to PL. There was no significant difference in time to exhaustion between the lactate treatments (p=0.09). Consumption of 120 or 300 mg lactate/kg bm by endurance-trained subjects increased blood HCO3- and improved exercise performance during high-intensity exercise bouts of approximately 150–180 s. However, consuming 300 mg lactate/kg bm provided no clear ergogenic effect compared to consuming 120 mg lactate/kg bm.