感染症と治療ジャーナル

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Microbiological Aspects of Peritonitis in Patients on Continuous Ambulatory Peritoneal Dialysis: A Monocentric Five Years Follow up Study

Travar M, Vlatkovic V and Vojvodic D

Peritonitis is a serious complication of continuous ambulatory peritoneal dialysis (CAPD). CAPD peritonitis usually occurs due to contamination by bacteria from the skin or the environment of the inserted catheter. The aim of this study was to analyze data about microbial cause of peritonitis in patients on CAPD monitored at University Clinical Centre of Republic of Srpska, Bosnia and Herzegovina in five years period, from October 2010 till October 2015. In the five-year period 69 samples of peritoneal dialysate were examined. The most common isolates were Gram +ve bacteria: Staphylococcus aureus in 9 cases (32.1%), coagulase-negative Staphylococcus 5 (17.6%) and the Gram -ve bacteria Escherichia coli 4 (14.2%) and Enterobacter 3 (10.7%). In one case Candida spp. (3.6%) was isolated. All the Gram positive isolates were sensitive to ciprofloxacin and vancomicin. Among Staphylococcus spp. there were no methicillin resistant strains. The findings of culture of peritoneal dialysate is important for the proper choice of antimicrobial therapy. The use of systemic vancomycin and ciprofloxacin administration is a simple and efficient first-line protocol antibiotic therapy for PD peritonitis.