当社グループは 3,000 以上の世界的なカンファレンスシリーズ 米国、ヨーロッパ、世界中で毎年イベントが開催されます。 1,000 のより科学的な学会からの支援を受けたアジア および 700 以上の オープン アクセスを発行ジャーナルには 50,000 人以上の著名人が掲載されており、科学者が編集委員として名高い
。オープンアクセスジャーナルはより多くの読者と引用を獲得
700 ジャーナル と 15,000,000 人の読者 各ジャーナルは 25,000 人以上の読者を獲得
GirmaMulisa, Lakew G Selassie, Godana Jarso, Teklu Shiferew, Adinew Zewdu, Wake Abebe, Feleke Belachew and Tsegaye Sewunet
Background: The beta-lactam groups of antibiotics are the largest group of antibacterial agents used in clinical practice and they are frequently prescribed. The wide use of these antibiotics leads to the emergence and spread of resistant bacterial pathogens that produce the extended-spectrum β-lactamases (ESBL). Now days ESBLs producer bacteria are a common encounter in clinical practice and their prevalence varies from local to global. The aim of this study was to determine the prevalence of ESBL producing bacterial pathogens among Enterobacteriaceae isolates at Adama Hospital, Ethiopia.
Methods: Across sectional study was conducted from May 1, 2013-June 1, 2014 at Adama Teaching Hospital. A total of 384 consecutive non-repeat culture isolates were obtained from different clinical specimens of from patients visiting the Hospital. Bacterial strains were isolated following standard bacteriological techniques of American Society of microbiology. Antimicrobial susceptibility test was determined using Kirby-Bauer disk diffusion method and ESBL production was detected by modified double disc synergy test as stated on clinical and laboratory slandered institute. Data was analyzed using SPSS version 20.
Results: A total of 133 bacterial strains were isolated of which Enterobacteriaceae account for 68/133(51.1%). Twenty one isolates from the Enterobacteriaceae were suspected for ESBL production and 17/21 (80.95%) of them were confirmed to produce it with the overall prevalence of ESBL producers within the Enterobacteriaceae is 17/68 (25%). E. coli with the prevalence of 10/35 (28.57%) is the leading ESBL producer while Proteus species, Klebsiella species, E. cloacae and Citrobacter species accounted for 3/9 (33.3%), 2/8 (25%), 1/3 (33.3%) and 1/3 (33.3%) respectively.
Conclusion: The prevalence of ESBL producing Enterobacteriaceae was high among the clinical isolates of Adama Hospital Medical College. Because microbiology laboratories are limited in Ethiopia, the problem may go beyond expectation before it is unraveled. Thus routine screening of ESBL producing microorganisms from clinical samples should be considered where applicable.