当社グループは 3,000 以上の世界的なカンファレンスシリーズ 米国、ヨーロッパ、世界中で毎年イベントが開催されます。 1,000 のより科学的な学会からの支援を受けたアジア および 700 以上の オープン アクセスを発行ジャーナルには 50,000 人以上の著名人が掲載されており、科学者が編集委員として名高い
。オープンアクセスジャーナルはより多くの読者と引用を獲得
700 ジャーナル と 15,000,000 人の読者 各ジャーナルは 25,000 人以上の読者を獲得
Vivig Shantha Kumar, Vignarth Shantha Kumar
Bacterial meningitis remains an overwhelmingly serious disease worldwide, associated with a considerably high incidence of long term neurological morbidity or even death. Despite the institution of appropriate antibiotic therapy over recent years, these therapeutic advances have failed to produce a corresponding reduction in neurological complications. Amongst the long-term neurological sequelae in bacterial meningitis, the most important sequelae include cerebrovascular disease and brain edema with subsequent increases in intracranial pressure. Recent experimental evidence suggests that live meningeal organisms account for only a minor degree of neurological injury in models of bacterial meningitis. More importantly, bacterial derived products, including toxic cell wall fragments and endotoxins, persistent and accumulative in the subarachnoid space following bactericidal killing by antibiotics or a sustenance of bacterial invasion and subarachnoid inflammation represent highly active elements capable of initiating adverse neuronal injury. This, in conjunction with other pathophysiological alterations in the central nervous system augments cerebral edema formation, which begins to increase during the acute phase of infection and progressively continues to increase over the disease course to culminate in dangerously elevated intracranial pressure levels, secondarily accounting for a high incidence of morbidity and mortality.