当社グループは 3,000 以上の世界的なカンファレンスシリーズ 米国、ヨーロッパ、世界中で毎年イベントが開催されます。 1,000 のより科学的な学会からの支援を受けたアジア および 700 以上の オープン アクセスを発行ジャーナルには 50,000 人以上の著名人が掲載されており、科学者が編集委員として名高い
。オープンアクセスジャーナルはより多くの読者と引用を獲得
700 ジャーナル と 15,000,000 人の読者 各ジャーナルは 25,000 人以上の読者を獲得
Gallegos Ivan, Carrasco Gonzalo, Fernandez Cristina, Castillo Octavio and Valdevenito Raul
Introduction: Renal Oncocytoma (RO) and Chromophobe Renal Cell Carcinoma (ChCCR) are within spectrum of “eosinophilic renal neoplasms” that can share morphological features. In some instances, it can be challenging differentiate both entities based only on the HE. For this reason, complementary ancillary techniques are needed.
Methodology: Sixteen RO cases and 21 ChCCR cases were evaluated for macroscopic and microscopic features, defining their architectural, nuclear and special stains criterion. Hale`s Coloidal Iron (HCI), Citokeratin 7 and CD15 were performed.
Results: Significant (p<.001) morphological differences were the pattern of grown (16/16 RO nested type vs 19/21 ChCCR diffuse type), nuclear morphology (“raisinoid” nuclei: 0/16 RO vs. 19/21 ChRCC) and presence of mitotic figure (0/16 RO vs. 16/21 ChCCR). Special stains showed that HCI was positive in 2/16 cases of RO and 20/21 of ChCCR, CK7 was positive in 1/16 cases of RO and 18/21 of ChCCR and CD15 was positive in 13/16 RO and 4/21 of ChCCR (p<.001).
Conclusion: Main differences beetwen RO and ChCCR are respectively the pattern of grown (nested/diffuse), raisinoid nucleus (-/+), and presence of mitosis (-/+). Besides ancillary techniques show HCH (-/+), CK7 (-/+) and CD15 (+/-). The ancillary panel of stains is very easy to perform and useful to achieve the correct diagnosis.