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Rift Valley Fever Virus: A Real Bioterror Threat

Robert B Mandell and Ramon Flick

Rift Valley fever virus is recognized as an important bioterror and agroterror threat to Western countries including the United States. Once introduced, the virus would be readily spread by native mosquito populations and potentially become endemic. While infection often results in severe morbidity and mortality in both humans and livestock, there are currently no FDA or USDA-licensed vaccines. The development of effective countermeasures and implementing surveillance and diagnostic capabilities are critical. Ultimately, the presence of RVFV would lead to severe long-term negative impacts for healthcare, agricultural and travel economic sectors.