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Smoking and Thyroid Dysfunction: A Systematic Review and Meta- Analysis

Dr. Shattuck Hannan

The purpose of this study was to investigate any connections between smoking behaviour and thyroid volume and function in Jeddah. The King Abdul-Aziz University Hospital's Radiology Department screened a total of 226 volunteers, 128 of whom were men and 98 of whom were women. They were divided into smokers and non-smokers; there were 99 smokers, 48 of whom smoked cigarettes and 51 of whom smoked shisha, and 127 non-smokers. A questionnaire was distributed at the radiology department to collect the data. 166 subjects underwent thyroid ultrasounds and thyroid function tests, and the results were analysed with SPSS version 22 and Microsoft Excel. The study was conducted using random selection, and the results showed that the majority of cases were in the 20 to 30 year age range, high body mass index (BMI) was 33.1 kg/m2 in those over 60, and the highest percentage of smokers was in the 20 to 30 year age range (40.02%). The thyroid was imaged by ultrasonography, which revealed 96 (58%) normal cases, 46 (28%) abnormal "solid" cases, and 24 (14%) abnormal "cyst" cases. In comparison to those who did not smoke cigarettes or shisha (47.9% and 47.3% respectively), a smaller percentage of smokers of both (15.4% and 5.6%) had an enlarged thyroid gland. For smoking cigarettes and shisha, the difference between these frequencies was statistically significant (Chi-square = 9.446 and 11.424, p = 0.002 and p = 0.001, respectively). As a result, it may be inferred from this study's findings that there are no significant direct correlations between smoking and thyroid volume or function. Yet, it is usually advised against smoking because of other known risks.

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