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Understanding Pathophysiology of Marburg Hemorrhagic Fever (MHF)

Tiwari VK, Akhil KV

The Transmission of a treacherous infectious disease threatens not merely a local population but the world at mass as the result of immigration and increased and faster pace. Any epidemics elicit considerable concern and demands that various precautionary methods be instituted and that the disease be eradicated as quickly as possible. Marburg haemorrhagic fever (MHF) is an old disease, one that may have been present for centenary and was identified decades ago. Fortunately, the disease, MHF was limited to a small geographical area, but the destruction of lives was much greater than that of many pandemics and was a warning of the number of factors, including fear, lack of knowledge regarding the disease, and deception, that can exacerbate the spread of disease and impact implementation of restraints. This article reviews the history of the disease caused by Marburg virus, pathophysiology and its biological components.