呼吸器疾患ジャーナル

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What Reactive Bronchopulmonary Mycosis Can Teach Us about Allergic Candida Sinusitis

Jen Singh

Severe allergic Bronchopulmonary fungi (ABPM) and allergic fungal nasal congestion (AFRS) are inflammatory diseases of the respiratory system brought on by type 1 and type 3 hypersensitivity reactions to fungus. The number of e penetration into the airway mucosa brought on by localized type 2 inflammation and concurrent viscid tears in the airways are the distinguishing characteristics of both disorders. In the lower and upper respiratory tracts, respectively, central bronchiectasis and bone erosion are caused by eosinophilic mucin-induced compression of nearby anatomical structures. Although the pathophysiology of several illnesses is similar, they also show observable variances. In terms of epidemiologic results, AFRS often manifests at a younger age than ABPM, has less difficult bronchial asthma, and has lower total immunoglobulin E levels in laboratory findings. Furthermore, despite their common genesis, the rarity of illustrates the differences between AFRS and ABPM by demonstrating the presence of sinio-bronchial allergic mycosis in both conditions. In order to evaluate what can be learnt about AFRS from ABPM, where more is known about the condition, this review tries to define the parallels and differences in the genesis of AFRS and ABPM.