ISSN: ISSN:2167-7964

OMICS 放射線学ジャーナル

オープンアクセス

当社グループは 3,000 以上の世界的なカンファレンスシリーズ 米国、ヨーロッパ、世界中で毎年イベントが開催されます。 1,000 のより科学的な学会からの支援を受けたアジア および 700 以上の オープン アクセスを発行ジャーナルには 50,000 人以上の著名人が掲載されており、科学者が編集委員として名高い

オープンアクセスジャーナルはより多くの読者と引用を獲得
700 ジャーナル 15,000,000 人の読者 各ジャーナルは 25,000 人以上の読者を獲得

インデックス付き
  • 索引コペルニクス
  • Google スカラー
  • Jゲートを開く
  • Genamics JournalSeek
  • 研究聖書
  • 電子ジャーナルライブラリ
  • レフシーク
  • ハムダード大学
  • エブスコ アリゾナ州
  • OCLC-WorldCat
  • SWBオンラインカタログ
  • 仮想生物学図書館 (vifabio)
  • パブロン
  • ジュネーブ医学教育研究財団
  • ICMJE
このページをシェアする

抽象的な

A FDG-PET and fMRI Study on Glucose Metabolism and Hemodynamic Response during Visual Attentional Performance in Schizophrenia

Jing Zhang, King-Wai Chu, Erin A Hazlett and Monte S Buchsbaum

This research investigated the correlation between regional cerebral glucose metabolism rate (rGMR) of [18F] fluorodeoxyglucose positron emission tomography (FDG-PET) and hemodynamic response of blood-oxygen-leveldependent (BOLD) fMRI in schizophrenia during visual attentional performance. PET, MRI and fMRI images of 17 unmedicated schizophrenia patients and 38 healthy controls were acquired. A visual attention task was administered during the FDG uptake period and during the fMRI scan. Statistical parametric mapping (SPM) analysis was performed on the PET and fMRI images. Hemodynamic response curves were extracted from the frontal and temporal cortices, Anterior Cingulate Cortex (ACC), caudate and thalamus. The Area under the Curve (AUC) was calculated for each region and correlated with rGMR obtained from PET images. The results indicated that (1) Although the spatial patterns of rGMR and hemodynamic response SPMs are different, the rGMR and hemodynamic responses were significantly correlated in the frontal and temporal cortex, anterior cingulate cortex, caudate and thalamus for all subjects; (2) The patterns of the correlations are different between schizophrenia patients and controls. These results confirm the findings of our previous PET and fMRI study during auditory attentional performance, suggesting that altered blood flowmetabolic processes during neuronal activities may underlie the attention deficits in schizophrenia, which may be useful for the early diagnosis of schizophrenia.